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ARCHES
ENZAMET
STAMPEDE
ArmG
–
Abi-
LATITUDE
Active Arm
(+ LHRH)
Enzalutamide Enzalutamide
Abiraterone
+ prednisona
Abiraterone
+ prednisona
N
1100
1125
1917
1209
Docetaxel
√
√
-
-
Low Volume
√
√
√
-
High Volume
√
√
√
√
Control
LHRHa
LHRHa
+ NSAA
LHRHa
LHRHa
1ary Endpoint
rPFS
OS
OS
OS & rPFS
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