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[Others -> discussion] [BMk+]

Q

P

Trial arm

2006200720082009201020112012201320142015201620172018201920202021202220232024

SOC+metformin

K

K

SOC+tE2

L

L

SOC+rucaparib [BMk+]

M

M

[Others -> discussion] [BMk+]

P

N

G

G

SOC+abi

B

B

SOC+zoledronic acid

C

C

SOC+docetaxel

D

D

SOC+celecoxib

E

E

SOC+zoledronic acid+docetaxel

F

F

SOC+zoledronic acid+celecoxib

A

A

Standard-of-care (SOC) = ADT (+/-RT)

H

H

SOC+M1|RT {M1}

J

J

SOC+enz+abi

(+/-docetaxel)

STAMPEDE