Enzalutamide
160 mg QD
+ LHRHa
(or orchidectomy)
until progression
n=1125
Metastatic prostate cancer
ECOG 0–2
•
First line
•
De Novo/Relapsed
•
Low & High volume
•
Docetaxel
–
early- allowed
NSAA + LHRHa
(or orchidectomy)
until progression
R
1:1
Phase III Randomized study in mHSPC