19 / 46
Enzalutamide
160 mg QD
+ LHRHa
(or orchidectomy)
until progression
n=1125
Metastatic prostate
cancer
ECOG 0–2
Commencing ADT
NSAA + LHRHa
(or orchidectomy)
until progression
R
1:1
Primary Objective
-
OS
Secondary Objectives
-
PSA PFS
-
Clinical PFS
-
Adverse Events
-
Health-related QoL
-
Healthcare resource cost-
effectivenes
Secondary Objectives
-
PSA PFS
-
Clinical PFS
-
Adverse Events
-
Health-related QoL
-
Healthcare resource cost-
effectivenes
Phase III Randomized study in mHSPC