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Development of an accurate and
reproducible assay to measure
the plasma AR
Carreira et al Sci Transl Med 2014
Definition
References
Refinement of assay and
retrospective evaluation of
association with outcome in a
prospectively collected set
Prospective validation of the
correlation between Plasma AR
and clinical outcome
-Clinical trial with randomization
defined by the Plasma AR
-Enrichment/selection for novel
therapies by the Plasma AR
Discovery &
Assay Development
Qualification
Stage I
Stage II
Stage I
Stage II
Romanel et al Sci Transl Med 2015
Conteduca V. Et al. Ann Oncol 2017
To be developed
Clinical
Practice
E. González Billalabeitia. PCAN 2018