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53.1% of patients

experienced a

decrease from

baseline

–100

–80

–60

–40

–20

0

20

40

60

80

100

Change From Bassline, %

Maximum Change

Asia

Rest of world

Total population

6-month OS rate: 66%

Median OS: 11.4 months (95% CI, 5.7-NR)

OS

0

10

20

30

40

50

60

70

80

90

100

0

2

4

6

8

10 12 14 16

Time, months

Overall Survival, %

n at risk

17

15

12

11

10

8

1

0

0

Asia

19

16

13

11

8

7

6

5

0

ROW

Asia

Rest of world

KEYNOTE-012: Gastric Cancer Cohort

Muro K et al. Lancet Oncol 2016

OR: 22%