ATTRACTION-2
: Overall Survival
Time (months)
Probability of Survival (%)
22
18
16
14
12
10
8
6
4
2
0
0
10
20
30
40
50
60
70
80
90
100
Hazard ratio, 0.63 (95% CI, 0.50–0.78)
P
< 0.0001
0
3
5
10
19
39
57
95
142
275
330
0
1
3
3
4
10
16
32
53
121
163
Nivolumab
Placebo
At risk:
20
193
82
Patients, n
Events, n
Median OS
[95% CI], months
12-Month OS Rate [95% CI],
%
Nivolumab
330
225
5.32 [4.63–6.41]
26.6 [21.1–32.4]
Placebo
163
141
4.14 [3.42–4.86]
10.9 [6.2–17.0]
Kang ASCO GI 2017