47 / 56
Data cutoff: April 21, 2017.
Cohort 1: PFS and OS by PD-L1 Expression
No. at risk
0 2 4 6 8 10 12 14 16 18 20 22 24 26
100
90
80
70
60
50
40
30
20
10
0
0 2 4 6 8 10 12 14 16 18 20 22 24 26
100
90
80
70
60
50
40
30
20
10
0
148
PD-L1
+
89 39 27 21 20 7 6 4 2 1 0 0 0
148 124 92 69 57 50 36 26 23 10 5 1
PD-L1
–
109 48 16 10 7 5 1 0 0 0 0 0 0 0
109 79 55 46 38 28 18 10 4 4 3 1 1 0
Progression-Free Survival, %
Overall Survival, %
No. at risk
Time, months
Time, months
PFS
Median (95% CI)
6-mo rate
PD-L1
+
2.1 (2.0-2.1) mo
18.2%
PD-L1
–
2.0 (1.9-2.0) mo
9.9%
OS
Median (95% CI)
6-mo rate
PD-L1
+
5.8 (4.4-7.8) mo
48.4%
PD-L1
–
4.6 (3.2-6.5) mo
42.9%
0 0
Kang ESMO GI 2017