Overall Survival, %
Time
(months)
100
90
80
70
60
50
40
30
20
10
0
0
ENCO300 VEM
Censored patients
3 6 9 12 15 18 21 24 27 30 33 36 39
42 45 48
Patients at
risk
84
ENCO30
0
194 181 168 147 133 117 109 94 86 83 79 59 40 24 5 0 0
VEM 191 184 166 140 115 100 89 83 77 71 62 56 30 19 8 1 0
Median OS in months (95% CI)
ENCO300
VEM
23.5 (19.6–33.6)
16.9 (14.0–24.5)
HR (95% CI), 0.76 (0.58–0.98)
Nominal 2-sided
P
=0.033