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Plasma (21/9/2018):

N-counter: NRAS Q61H

KRAS Q61P

BRAF V600E

Plasma (21/9/2018):

Taqman: BRAF V600E (2,53%)

Rebiopsia (Biopsia SD):

NGS: BRAF V600E (1,86%)

Plasma (11/5/2018):

NGS: KRAS G12A (14%)

BRAF V600E (1,6%)

Biopsia inicial ( B17B3019):

NGS: BRAF V600E (22.7%)

11-5-2018

12-6-2018

23-7-2018

7-9-2018 21-9-2018

9-11-2018

Plasma (9/11/2018):

NGS: BRAF V600E (3%)

e

Mayo C, MA Molina (Rosell`s lab)

encorafenib+binimetinib