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*Only PD-L1-positive patients.

Ott PA, et al.

J Clin Oncol

. 2017

0

4

8

12

16

20

24

0

20

40

60

80

100

T im e , m o n th s

P r o g r e s s io n -F r e e S u r v iv a l, %

Num ber at risk 24

8

6

2

4

2

0

9

6

5

2

2

0

4

8

12

16

20

24

0

20

40

60

80

100

T im e , m o n th s

O v e r a ll S u r v iv a l, %

Num ber at risk 24

17

14

4

8

4

0

20

14

9

4

6

4

28.6% 23.8%

66.0% 37.7%

PFS

OS

Study phase

Line of

treatment

Regimen

Patients

ORR, % DOR, mo

PFS, mo

OS, mo

1b*

2

PEMBRO 10 mg/kg

24

33.3

19.4

1.9

9.7