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ORR and DOR

a

a

Per local investigator.

b

95% CI, 10.0–18.3%.

c

12.4–21.3%

0

5

10

15

20

Nivolumab Chemotherapy

ORR (%)

39/284

n/N:

47/285

Nivolumab Chemotherapy

CR

PR

13.7

b

16.5

c

13.4

16.1

0.4

0.4

ORR

33

Nivolumab

Chemotherapy

Nivolumab

(n = 39)

Chemotherapy

(n = 47)

Median DOR

8.3

4.5

(95% CI), mo

(7.0–12.6)

(4.1–5.8)

9

2

39

47

35

34

26

14

17

9

14

4

12

3

7

1

5

0

2

0

1

0

0

0

Patients in response (%)

100

80

60

40

20

0

0 3 6 9 12 15 18 21 24 27 30 33

Months

No. at risk

Nivolumab

Chemo