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Pujol J, et al. Ann Oncol 2018;29(suppl 5):Abstr 1664O

HR (adjusted) atezolizumab group = 2.26 (95%CI 1.30, 3.93); p=0.004

Time, months

0 1 2 3

5 6 7 8 9

4

Median follow-up: 13.7 months (95%CI 12.7, NR)

Chemotherapy (n=24): 4.3 (1.5, 5.9); 21 events, 3 censored

Atezolizumab (n=49): 1.4 (1.2, 1.5); 46 events, 3 censored

6-month PFS rate for atezolizumab group: 6.3% [0.0, 13.1]

Progression-free survival

1.0

0.8

0.6

0.4

0.2

0

Median PFS, months (95%CI)

PFS (ITT population)