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Treatment free survival (TFS) in IMDC intermediate/poor-

risk patients who discontinued protocol therapy

Time from treatment discontinuation (months)

0

6

No. at risk

NIVO+IPI

352

98

69

46

34

22

5

SUN

383

42

23

13

8

2

0

12

18

24

18 months 24 months

30

100

75

50

25

0

36

Patients free from second-line treatment (%)

NIVO+IPI

SUN

TFS,

Months

TFS rate (95% CI), %

NIVO+IPI

(N = 352)

SUN

(N = 383)

18

20 (16–26)

6 (4–9)

24

19 (15–24)

6 (4–9)

McDermott, ESMO 2018