22 / 43
Time from randomization to second-line treatment
initiation or death in all IMDC intermediate/poor-
risk patients
22
Time from randomization (months)
0
6
No. at risk
NIVO+IPI
425
305
225
197
167
140
53
1
SUN
422
260
157
112
82
58
27
0
12
18
24
18 months
24 months
30 months
30
100
75
50
25
0
36
42
Patients free from second-line treatment (%)
NIVO+IPI
SUN
Patients alive who had not
received second-line therapy
Time since
SUN
randomization,
(95% CI), %
months
(N = 422)
Shaded area around curves represents 95% CI
Time since
randomiza
tion,
months
NIVO+IPI,
(95% CI), %
(N = 425)
SUN
(95% CI), %
(N = 422)
18
48 (43–53) 28 (24–33)
24
41 (37–46) 20 (17–25)
30
36 (31–41) 16 (13–20)