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KRAS

Results in Perspective

1st

line

2nd

line

~40% of the ITT

Interaction test = 0.38

100% of the ITT

Interaction test = 0.51

~75% of the ITT

Interaction test = 0.13

Ince WL et al.

JNCI

. 2005;97:981-9; Kubicka S et al.

Ann Oncol

. 2013;24:2342-2349; Obermannova et al.

Ann Oncol

. 2016 ;27:2082-2090.

+ 4.4

+ 0.4

+ 2.5

+ 1.4

+ 3.3

+ 2.0

Tejpar, World GI 2017