20 / 34
BRAF
mutant 2
nd
-Line mCRC
Control arm in line with previously published trials
6
5,8 5,7
4,7 4,3 4,1
5,5
10,3
0
2
4
6
8
10
12
Cetux - CT
(1)
Cetux - CT
(2)
FOLIFIRI
(3)
FOLIFIRI -
Pani (3)
Cetux - CT
(4)
Cetux - Iri
(5)
FOLFIRI FOLFIRI -
Afli
mOS
1. De Roock W et al. Lancet Oncol. 2010;11:753-62; 2. Ulivi P et al.
J Transl Med
. 2012;10:87; 3. Peeters M et al.
J Clin Oncol
. 2014; 32:5s (suppl; abstr 3557);
4. Saridaki Z et al.
PLoS One
. 2011;6:e15980; 5. Loupakis F et al.
BJC
. 2009;101:715-21
n= 24
n= 12
n= 23
n= 22
n= 8
n= 13
n= 20
n= 16
VELOUR
Tejpar, World GI 2017