NEPA Conclusions
• The fixed-dose combination, single dose oral treatment:
– Is based on rigorous dosing studies (pre-clinical and clinical)
– Combines agents with long plasma half-lives and long durations of activity
– Is rigorously tested for safety
– Is associated with competitive antiemetic activity
• Multiple cycles
• Cisplatin
• “AC” Chemotherapy
• NEPA directly addresses the key issues of:
– Guideline compliance in prescribing
– Enhancing ease of patient adherence and education