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Complete Response Rates: Overall (0-120 hr) Over Multiple Cycles

- Highly and Moderately Emetic Chemotherapy -

Similar results observed for both the QAE and QME subsets

Ref: Gralla RJ et al. Ann Oncol. 2014; 25:1333 – 1339

81

86

91

90

92

91

76

81

87

88

86

86

0

20

40

60

80

100

Cycle 1 Cycle 2 Cycle 3 Cycle 4 Cycle 5 Cycle 6

Patients (%)

NEPA

APR + PALO

309

NEPA (n)

APR + PALO (n)

156

233

280

259

124

Full analysis population.

CR (no emesis, no rescue

medication)

103

57

81

96

90

44