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expression by
immunohistochemistry
TPS =
IC area PD-L1+
Total # of viable tumor cells
MIDS =
#PD-L1 stained immune cells
Total # of viable tumor cells
CPS =
#PD-L1 stained cells (tumor cells
lymphocytes, macrophages)
Total # of viable tumor cells
#PD-L1 stained tumor cells
Overall IC area
Tumor PD-L1+
Overall tumor area
TC =
IC =
Tumor
proportion score
Combined
positive
score
X 100
Mononuclear
immune cell
density
X 100
X 100
Tumor cell area
Tumor-
infiltrating
immune cells
area