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Trial

Enrollment

Treatment

Primary endpoint

PROSPER (NCT02003924)

1401

Enzalutamide 160 mg once daily vs

placebo

Metastasis-free survival

SPARTAN (NCT01946204)

1207

Apalutamide 240 mg once daily vs

placebo

Metastasis-free survival

ARAMIS (NCT02200614)

1509

Darolutamide 600 mg twice daily vs

placebo

Metastasis-free survival

M0 CASTRATION-RESISTANT PROSTATE CANCER:

THE RIGHT PATIENT FOR CLINICAL TRIAL