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Scher HI, et al. J Clin Oncol 2016;34:1402-1418

Clinical

Metastases:

Noncastrate

Clinically

Localized

Disease

Rising

PSA

Noncastrate

nmCRPC

mCRPC:

1st line

mCRPC:

2nd line

mCRPC:

“n” line

NO STANDARD THERAPY

Castration

+

Abiraterone/Docetaxel

Abiraterone

Enzalutamide

Docetaxel

Cabazitaxel

Radium-223

PROSTATE CANCER LANDSCAPE AND THERAPIES IN 2017

Castration