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Penson

11

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summary

eneral;

-being;

Figure 2. Association between longitudinal changes in HRQoL (FACT-P) and MFS

CI=confidence interval; EWB=emotional well-being; FACT-G=Functional Assessment of Cancer Therapy–General; FACT-P=Functional Assessment of Cancer Therapy–Prostate;

FAPSI=FACT Advanced Prostate Symptom Index; FWB=functional well-being; HR=hazard ratio; HRQoL=health-related quality of life; MFS=metastasis-free survival;

PCS=prostate cancer subscale; PCSP=prostate cancer subscale pain-related score; PSA=prostate-specific antigen; PWB=physical well-being; SWB=social/family well-being;

TOI=trial outcome index.

7)

9)

3)

4)

9)

0)

8)

2)

7)

8)

!

0.001

!

0.001

!

0.001

0.080

0.006

!

0.001

!

0.001

!

0.001

!

0.001

!

0.001

p-value

0.7

0.8

Domain

PWB

0.86 (0.81, 0.92)

FWB

0.94 (0.88, 1.01)

EWB

0.88 (0.78, 0.99)

SWB

0.99 (0.93, 1.07)

PCSP

0.92 (0.85, 1.00)

PCS

0.91 (0.86, 0.96)

FAPSI

0.84 (0.79, 0.91)

TOI

0.89 (0.83, 0.96)

FACT-G

0.95 (0.89, 1.00)

FACT-P total

0.93 (0.88, 1.00)

1.0

HR (95% CI)

!

0.001

0.091

0.041

0.887

0.047

!

0.001

!

0.001

0.002

0.066

0.039

p-value

0.9

1.1

Increased risk of metastasis

Decreased risk of metastasis

ASSOCIATION BETWEEN HEALTH-RELATED QUALITY OF LIFE

AND CLINICAL OUTCOMES IN PROSPER

Attard G, et al. J Clin Oncol 36, 2018 (suppl; abstr 5043)