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Talazoparib after Platinum or Nonplatinum in mBRCAg MBC
ABRAZO
COHORT 1
Litton J. SABCS 2017
Platinum-sensible for MBC
(no PD within 8 weeks of last dose of platinum)
COHORT 2
>3 non-platinum CHEMO for MBC
ORR 21%
ORR 37%
ORR
PFS