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Veliparib does not improve pCR when added to carboplatin

plus standard neoadjuvant chemo in TNBC (BrighTNess)

Loibl S. Lancet Oncol 2018

Paclitaxel + CBDCA + Velaparib → AC

Paclitaxel + CBDCA + PLACEBO → AC

n=624

Neoadjuvant

chemo for TNBC

Paclitaxel + PLACEBO + PLACEBO → AC