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Developing new antiemetic agents to address
recognized issues in controlling emesis
• Even with marked progress in effective antiemetic prophylaxis, many patients still experience
emesis with chemotherapy, particularly during the delayed phase
– Reasons for emetic failure include
:
• Patients are not always prescribed effective guideline-based antiemetic drug regimens
• Patients frequently do not adhere to delayed emesis regimens
• Antiemetic guidelines result in significant improvement in the control of emesis with better resource
utilization
• There is a need to enhance guideline-consistent practice and to assist patient adherence
An effective single dosing, all oral regimen given immediately prior to chemotherapy could provide
convenient care enhancing effectiveness