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1.Ramalingam SS, et al. J Clin Oncol. 2018; 2. Minari T et al. JTO 2018 [Epub ahead of print; 3. Yu HA, et al. Clin Cancer Res. 2013;19(8):2240-2247;

Acquired resistance mechanisms

1

st

vs 3

rd

Generation EGFR TKI