Valor clínico de la biopsia líquida de alta sensibilidad: real word data experience con OncoBEAM en CCRm

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Mutant allele fractions are frequently low in liquid biopsy
29%
21%
11%
39%
MAFs
0.01-0.1%
0.1-1%
>1%
>5%
Mutant RAS (n=61)
Concordance Study
(VHIO, ICO, H.Mar)
Median MAF Tumor
4% mBC Dawson et al., 2013
1.5% mCRPC Azad et al., 2015
4% mCRC Grasselli et al., 2017
6.6% NSCLC
Fairclough et al., J Clin
Oncol 34, 2016 (suppl;
abstr e23021)