Valor clínico de la biopsia líquida de alta sensibilidad: real word data experience con OncoBEAM en CCRm

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Real world data_ Baseline mCRC
47% RAS mutant (93/198)
Median concentration= 0,26 ng/ml [0,08-7,32] 100-fold
Median RAS MAF= 6,3% [0,01%-42%] 4200-fold
RAS
mutation
status
Anti-
EGFR
therapy
Tissue
blood
WT
Chemotherap
y
(e.g. FOLFIRI)
MUT
Monitoring of
RAS mutation
status
T0 T1 T2
MUT
No tissue
Anti-EGFR Re-challenge?