Critical aspects in implementation of liquid biopsy in the clinics
ctDNA
shedding
Intratumor
heterogeneity
Targeted
therapies
Tumor load
Met locations
Necrosis, other
biological processes
Clonality
mCRC: APC, KRAS vs
BRAF, PIK3CA
Selection
mCRC: anti-EGFR, RAS
clones
mCRC