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Treatment Flow 2

nd

line –

Non-SCC

PRE-TREATED ADVANCED NON-SQUAMOUS NSCLC

PD-L1

POSITIVE

I-O

docetaxel

+ ramucirumab

docetaxel

+ nintedanib

Erlotinib ?

PD-L1 NEGATIVE

Fit Patient

docetaxel

+ ramucirumab

docetaxel

+ nintedanib

I-O

Unfit Patient

I-O

erlotinib?

NSCLC