Usando inhibidores de PARP en el tratamiento de las pacientes con cáncer de ovario: Cómo, Cuando, A quién y Por qué

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ARIEL4 : international, multicentre, randomised phase 3 study evaluating rucaparib vs SOC
chemotherapy as treatment for patients with germline or somatic BRCA1- or BRCA2-mutated,
relapsed, high-grade OC who have received ≥2 prior chemotherapy regimens
ClinicalTrials. Gov: NCT02855944
N= 345 patients