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Integrated Efficacy Results:

PFS in Specified Groups According to Platinum Sensitivity

Median PFS ranged from 5.3 to 11.1 months, based on sensitivity to most recent platinum regimen

Median (months)

95% CI

11.1

7.3–12.8

7.4

5.5–Not reached

5.3

1.7–Not reached

Platinum-sensitive (n=79)

Platinum-resistant (n=20)

Platinum-refractory (n=7)

Censored

+

0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Months

0

0.1

0.2

0.3

0.4

0.5

0.6

0.7

0.8

0.9

1.0

Probability of PFS

Platinum-sensitive

At risk (events)

79

(0)

65

(9)

60

(11)

38

(26)

30

(29)

21

(32)

14

(38)

8

(43)

3

(44)

3

(44)

2

(45)

0

(45)

Platinum-resistant 20

(0)

15

(3)

7

(4)

4

(6)

1

(6)

0

(6)

Platinum-refractory 7

(0)

5

(2)

2

(4)

1

(5)

71

(4)

17

(3)

5

(2)

Oza AM et al.

Gynecol Oncol

. 2017;147:267–275