43 / 50
5HT3
DEX
APR
5HT3
DEX
APR
PALO
DEX
DEX
+
+
+
+
+
DEX = DEXAMETHASONE
NK1 = neurokinin receptor
antagonist
A Modest Proposal for Updating Antiemetic Risk Categories by Chemotherapy
for Guideline Use: Delayed Emesis
EMETIC RISK GROUP
ANTIEMETICS
High
Moderately-High
(60% -90%)…ie…AC, Carbo,
Oxali, more…
Moderate (other than AC)
Low
No routine prophylaxis
Minimal
No routine prophylaxis
DEX
NK1* or none
±
DEX
* NOTE
: if NEPA (with netupitant), rolapitant, aprepitant 165 mg or fos-aprepitant 150mg used on Day 1 – no further NK1 but, continue NK1 if 3-day aprepitant regimen is used
+
±
DEX
i.e.: Cisplatin
…thus…no delayed emesis meds needed if:
1) long-acting NK
1
RA is used
2) steroid sparing results apply to all of these categories
NK1* or none