72 / 116
Splicing forms p61BRAFV600
•
6/19
patients: 61kd variant form of BRAF(V600E) that lacks exons 4-8, a region
•
It could be sensible to higher dose or combination, unless it is also observed
in pts with combined treatment (Hartsoughet al , 2014)
Poulikakos P. Nature 2011