48 / 63
Looking for new subrogate
§
The association between <10%
residual tumor tissue and survival is
strong
§
The variable degree of pathologic
response statistically tracks with the
impact on survival
§
The significant association between
<10% viable tumor and survival,
captures a substantial part of the
effect of the treatment on survival
NADIM
N
%
Major
response
1
Complete
response
24
18
80.0
75.0
Less < 90%
6
20.0
Total
30
100.0