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Subgroup Analysis by PD-L1 Status

Important facts regarding PD-L1 status:

PD-L1 testing was not required

37% of patients with unknown PD-L1 status

PD-L1 status was obtained pre-CRT (getting a sample post-CRT medically not feasible)

PD-L1 expression-level cutoff of 1% was part of an

unplanned post-hoc analysis requested by a health authority

Overall Survival with Durvalumab versus Placebo after

Chemoradiotherapy in Stage III NSCLC: Updated Results from PACIFIC