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1.0

0.9

0.8

0.7

0.6

0.5

0.4

0.3

0.2

0.1

0.0

3

6

9

12

15

18

21

24

27

30

33

36

39

Probability of Progression-free Survival

Time from Randomization (months)

No. at Risk

Durvalumab

476

377

302

268

213

188

163

143

116

83

43

23

1

0

Placebo

237

163

106

86

67

55

46

39

32

24

10

5

0

0

PFS HR = 0.51

95% CI, 0.41–0.63

34.4%

49.5%

55.7%

26.7%

No. of events /

No. of patients (%)

Median PFS

(95% CI)

months

Durvalumab

243/476 (51.1)

17.2 (13.1–

23.9)

Placebo

173/237 (73.0)

5.6 (4.6–7.7)

0

Overall Survival with Durvalumab versus Placebo after

Chemoradiotherapy in Stage III NSCLC: Updated Results from PACIFIC