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CHECKMATE 214: Progression-free survival per
investigator in responders
37
•
CheckMate 214
Months
0
6
No. at risk
NIVO+IPI
178 175 164 142 126 117 109 94 87 81 76 47 17 3 0
SUN
124 121 107 90 75 66 55 47 35 25 19 12 5 0 0
No. at risk
NIVO+IPI
49 49 46 42 38 36 31 29 28 26 23 20 8 1 0
SUN
62 62 61 58 55 51 47 40 37 36 32 28 13 2 0
12 18 24 30
1.0
0.8
0.9
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0.0
36
3
9
15 21 27 33
42 39
Progression-free survival
(probability)
Months
0
6
12 18 24 30
1.0
0.8
0.9
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0.0
36
3
9
15 21 27 33
42 39
Progression-free survival
(probability)
NIVO+IPI
NIVO+IPI
SUN
SUN
Intermediate/Poor-Risk Complete/Partial Responders
Favorable-Risk Complete/Partial Responders
60%
41%
64%
62%
NIVO+IPI
(N = 178)
SUN
(N = 124)
Events, n (%)
72 (40.4)
80 (64.5)
PFS, median
(95% CI), months
NR (29.0–
NE)
20.5 (15.4–
24.5)
NIVO+IPI
(N = 49)
SUN
(N = 62)
Events, n (%)
22 (44.9)
36 (58.1)
PFS, median
(95% CI),
months
36.4 (20.7–
NE)
31.9 (26.4–
37.2)