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Continuous learning = improving management
TRAEs, n (%)
All grades
(%)
Grade ≥3
(%)
All grades SELECT
(%)
Grade ≥3 SELECT
(%)
All
96
48
97.3
75.9
Fatigue
61
8
59.0
9.2
Weight loss
59
0
46.4
9.6
Hypertension
67
35
67.8
41.8
Diarrhoea
45
1
59.4
8.0
Decreased appetite
36
1
50.2
5.4
PPE
28
0
31.8
3.4
Stomatitis
24
3
35.6
4.2
Nausea
18
0
41.0
2.3
Dysphonia
16
0
24.1
1.1
Myalgia/Althralgia
12
0
18.0
0
Epistaxis
15
0
0
0
Berdelou A, et al. Thyroid. 2017
Dose reduction: 68%
Dose interruption: 82%
Discontinuation: 14%
Dose reduction: 59%
Dose interruption: 31%
Discontinuation: 16%