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P I/II Indoximod (IDO inh) + Gem-Abx in mPC

(Bahary N, ASCO 2018)

150 pt

RR: 46%

Median OS 10.9 m (obj 12.1 m not reached)

P III KN-252: Pembro +/- epacadostat (IDO inh)

in advanced melanoma