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A phase I study of an agonist CD40 monoclonal antibody

(CP-870,893) in combination with gemcitabine in patients with

advanced pancreatic ductal adenocarcinoma

Beatty et al, Clin Cancer Res 2013

Additional trials with CD40 agonist in monotherapy or combinations

with gem-based QTA are ongoing (NCT02588443, NCT02829099)

N 28

RR 19%