7 / 38
1980
1990
2000
2010
STZ in pNET
Octreotide SC
IFN-alpha
Lanreotide SC
PROMID
Octreotide LAR
Midgut
RADIANT-3
Everolimus
pNET
Phase III
Sunitinib
pNET
CLARINET
Lanreotide AG
GEP NET
2015
RADIANT-2
Everolimus
mNET w/CS
ELECT
Lanreotide
Symptom control
RADIANT-4
Everolimus
GI & Lung NET
2019
TELESTAR
Telotristat
CS
NETTER-1
177Lu-DOTATATE
NET
FDA and/or EMA approval
Not approved
Carcinoid syndrome
Octreotide LAR
GEP/UK NET
THERAPEUTIC OPTIONS IN NETs
Approval, phase II RCT
CAPTEM
pNET