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SOMATOSTATIN ANALOGS

TIME OF SSA TREATMENT INITIATION & LONG TERM SURVIVAL

Crossover from placebo to octreotide LAR in

88.4% after median time of 9.2 months (2-82)

Caplin M, et al. Endocrine-Related Cancer 2016; 23:191-199

Rinke A, et al. Neuroendocrinology 2017;104:26–32

Estimated mPFS LAN-LAN = 32,8 m

Estimated mPFS PBO-LAN =14,0 m