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CURRENT TREATMENT LANDSCAPE OF ADVANCED NETs

Indication

ANTIPROLIFERATIVE

CARCINOID SYNDROME

Treatment

Octreotide Lanreotide 177Lu-

DOTATATE

Streptozocin

TMZ Sunitinib Everolimus Octreotide Lanreotide Telotristat

Lung

RADIANT4

Stomach

CLARINET

RADIANT4

Pancreas

CLARINET

RADIANT3

Small

bowell

Appendix

PROMID CLARINET NETTER1

ECOG2211 Phase III

RADIANT4

Colon

CLARINET NETTER1

RADIANT4

Rectum

CLARINET

RADIANT4

Unknown

primary

RADIANT4