Quality of Life and survival in NSCLC: Impact of early
palliative intervention (at the start of chemotherapy)
Temel
et al. NEJM
2010
-5.0
-2.5
0
5.0
7.5
Standard care
FACT-L
Mean change
2.5
Early palliative
care
0
10
20
40
50
HADS-D
12-week outcomes of
assessments of mood
Patients with
mood symptoms (%)
30
HADS-A PHQ-9
Standard care
Early palliative care
0
20
40
80
100
0
Patients surviving (%)
60
10
20
30
40
Months
Standard care
Early palliative care
1:1 Randomization
N = 151
Initial chemotherapy
Survival:
11.6 vs 8.9 months
p
=0.02