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Toxicities, neoadjuvant (n=45)

Hematological

GRADE

1

2

3

4

Total

N % N % N % N % N %

Anemia

5 11.1 2 4.4 0 0.0 0 0.0 7 15.6

Febrile neutropenia

0 0.0 0 0.0 1 2.2 0 0.0 1 2.2

Neutropenia

0 0.0 1 2.2 2 4.4 1 2.2 4 8.9

Thrombocytopenia

2 4.4 1 2.2 0 0.0 0 0.0 3 6.7

Non-hematological

N % N % N % N % N %

Fatigue

12 26.7 6 13.3 1 2.2 0 0.0 19 42.2

Alopecia

2 4.4 11 26.7 0 0.0 0 0.0 14 31.1

Nausea

11 24.4 1 2.2 0 0.0 0 0.0 12 26.7

Arthralgia

8 17.8 1 2.2 0 0.0 0 0.0 9 20.0

Diarrhea

6 13.3 2 4.4 0 0.0 0 0.0 8 17.8

Decreased appetite

7 15.6 0 0.0 1 2.2 0 0.0 8 17.8

Vomiting

3 6.7 3 6.7 0 0.0 0 0.0 6 13.3

Myalgia

4 8.9 2 4.4 0 0.0 0 0.0 6 13.3

Constipation

3 6.7 2 4.4 0 0.0 0 0.0 5 11.1

Pruritus

4 8.9 1 2.2 0 0.0 0 0.0 5 11.1