35 / 63
N
%
Major
response
1
Complete
response
24
18
80.0
75.0
Less < 90%
6
20.0
Total
30
100.0
Pathological response
1
Major pathological response defined as
<10% viable tumor cells in the resected
specimen.
•
Median patient follow-up = 4.1 months, range 0.2-14.6 months.
•
None of the patients have suffered recurrence.
The following factors were considered to identify factors that
potentially influence pathological response (complete and major):
•
Age
•
Gender
•
Performance status
•
Smoking status
•
Comorbidities
•
Clinical stage
•
Clinical response
•
Primary tumor site (right vs left)
•
Histology (adenocarcinoma vs squamous)
•
Nodes involvement (yes/no)
•
Nodes resected and hematological
toxicities grade 3-4
Each factor was compared between patients with pathological
response (complete and major) vs those with no response. Factors
with p<0.1 were considered potential factors for a logistic regression
analysis (N=30).
No significant logistic regression models were obtained.