7 / 46
mHSPC
Inclusion Criteria Control
Active Arm
N 1ary
Endpoint
Com.
ARCHES
NCT02677896
Naïve
or
ADT + Doc x6 <2 m
ADT
Ctrl +
Enza
1150 rPFS
Oct
2018
ENZAMET
NCT02446405
Naïve
ADT
±
Doc
ADT
±
Doc +
Enza
1125
OS
Sep
2020
PEACE-1
NCT01957436
Naïve
ADT + Doc
ADT + Doc +
Abi
ADT + Doc +
RT
ADT + Doc +
Abi + RT
1168 OS & rPFS
Oct
2018
TITAN
NCT02489318
Naïve* or
ADT + Doc x 6 <2 m
ADT
ADT +
Apalutamide
1052 OS & rPFS Nov
2020
ARASENS
NCT02799602
Naïve
ADT + Doc
ADT + Doc +
ODM-201
1303
OS
Aug
2022
SWOG 1216
NCT01809691
Naïve
ADT +
bicalutamide
ADT + TAK-700
1313
OS
Mar
2022
*Excludes Visceral or LN only metastasis
.