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Estudios fases III: 1ª LINEA y mantenimiento

Atezolizumab

+ Cis/Carbo-Gem x6

Atezolizumab

Atezolizumab

Cis/Carbo-Gem x6

Pembrolizumab

+ Cis/Carbo-Gem x6

Pembrolizumab

Pembrolizumab

Cis/Carbo-Gem x6

Cis/Carbo-Gem x4-6

Avelumab

Observation

Durvalumab-

Tremelimumab x4

Durvalumab

Cis/Carbo-Gem

Nivolumab-Ipilimumab

Nivolumab + CisGem

Cis/Carbo-Gem

Durvalumab

Nivolumab

Nivolumab

CHECKMATE 901

DANUBE

KEYNOTE 361

JAVELIN BLADDER 100

IMVIGOR 130